By sifting through hundreds of millions of mutations lurking in the genomes of more than 12,000 tumours, researchers have identified patterns of DNA changes that could offer clues to the genetic and environmental causes of cancer. The study is the largest of its kind. It adds dozens of entries to the growing catalogue of ‘mutational signatures’ that accompany cancer, and could, in some cases, help clinicians to select the best treatments for individuals.
Nature | 4 min readReference: Science paper